Effect of Temperature and Strain Rate on the Hot Deformation Behaviour of Ferritic Stainless Steel

Metals and Materials International - The flow behaviour and microstructure characteristics of a ferritic stainless steel were investigated using plain strain compression test on a Gleeble 3500...     

选择性激光粉末烧结的成型过程研究

本文通过对选择性激光粉末烧结的成型过程的分析,讨论了粉床特性、材料热物性以及激光热载荷对成型件质量的影响,并采用有限元的方法对其三维温度场分布进行了模拟计算,     

Steady-state response of the parametrically excited axially moving string constituted by the Boltzmann superposition principle

Summary.  The steady-state transverse vibration of a parametrically excited axially moving string with geometric nonlinearity is investigated in this paper. The Boltzmann superposition principle is employed to characterize the material property of the string. The method of multiple scales is applied directly to the governing equation, which is a nonlinear partial-differential-integral equation. The solvability condition of eliminating the secular terms is established. Closed form solutions for the amplitude and the existence conditions of nontrivial steady-state response of the summation resonance are obtained. Some numerical examples showing effects of the viscoelastic parameter, the amplitude of excitation, the frequency of excitation, and the transport speed are presented. Received February 12, 2002; revised October 25, 2002 Published online: May 8, 2003 The research was supported by the National Natural Science Foundation of China (Project No. 10172056).     

Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML

Relapse after autologous bone marrow transplantation for chronic myelogenous leukemia (CML) can be due either to the persistence of leukemia cells in systemic tissues following preparative therapy, or due to the persistence of leukemia cells in the autologous marrow used to restore marrow function after intensive therapy. To help distinguish between these two possible causes of relapse, we used safety-modified retroviruses, which contain the bacterial resistance gene NEO, to mark autologous marrow cells that had been collected from patients early in the phase of hematopoietic recovery after in vivo chemotherapy. The cells were then subjected to ex vivo CD34 selection following collection and 30% of the bone marrow were exposed to a safety-modified virus. This marrow was infused after delivery of systemic therapy, which consisted of total body irradiation (1,020 cGy), cyclophosphamide (120 mg/kg), and VP-16 (750 mg/m2). RT PCR assays specific for the bacterial NEO mRNA, which was coded for by the virus, and the bcr-abl mRNA showed that in two evaluable CML patients transplanted with marked cells, sufficient numbers of leukemia cells remained in the infused marrow to contribute to systemic relapse. In addition, both normal and leukemic cells positive for the retroviral transgenome persisted in the systemic circulation of the patients for at least 280 days posttransplant showing that the infused marrow was responsible for the return of hematopoiesis following the preparative therapy. This observation shows that it is possible to use a replication-incompetent safety-modified retrovirus in order to introduce DNA sequences into the hematopoietic cells of patients undergoing autologous bone marrow transplantation. Moreover, this data suggested that additional fractionation procedures will be necessary to reduce the probability of relapse after bone marrow transplantation in at least the advanced stages of the disease in CML patients undergoing autologous bone marrow transplantation procedures.     

提高水电供区供电质量的思考

本文通过调查了解，分析了小水电供区供电质量存在的问题，并结合安徽水电岳西有限责任公司所属电网实际情况提出一些解决方案。     

北京火车站抗震鉴定与加固技术

北京火车站是首都重要的标志性建筑之一 ,195 9年建成 ,当时按 7度设防考虑 ,存在着许多不符合抗震要求的问题 ,一些设施也明显不能满足现代使用功能要求。北京火车站抗震加固与改造设计项目组 ,运用多种先进的加固手段 ,在保持原建筑外貌不变的前提下 ,实现了抗震能力和改善使用功能的协调 ,取得了大型公共建筑加固改造的新经验     

Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family

By using a mRNA differential display technique to search for salicylate suppressible genes, we identified a cDNA in human foreskin fibroblasts, which by GenBankTM DNA data base search shows sequence homology to the recently reported cullin/Cdc53 (CUL) family genes, especially CUL-3. We have cloned the full-length human CUL-3 (Hs-CUL-3) cDNA. It encodes a 768-amino acid polypeptide and has a predicted molecular weight of 88,939. The amino acid sequence of Hs-CUL-3 shows 46% homology to that of its Caenorhabditis elegans ortholog, Ce-CUL-3, and 27 and 23% to that of Hs-CUL-1 and Hs-CUL-2, respectively. Northern blot analysis showed that phorbol 12-myristate 13-acetate increased the expression of Hs-CUL-3 mRNA in a concentration- and time-dependent manner, and this increase was inhibited by sodium salicylate. Hs-CUL-3 widely expressed in human tissues and its expression in cultured COLO205 colon cancer cells was increased when compared with that in normal colon cells. It is likely that Hs-CUL-3 is involved in cell proliferation control.     

磁悬浮硬盘转子控制系统中时序电路测试技术

为提高磁悬浮硬盘转子控制系统的可靠性，提出了对时序芯片的测试方法：手工测试和计算机辅助测试；及时时序电路逻辑功能的两种检测技术；基于状态表的测试技术和自动检测技术。对于时序芯片，手工测试方法效率较低，计算机辅助测试方法适用范围更广；对于电路逻辑功能，基于状态表的测试技术操作相对困难，但无须增加额外测试电路；自动检测技术操作简单，且测试速度快，但需要增加辅助检测电路。时序电路测试技术对保证悬浮硬盘转子各组成部分协同工作十分重要。     

正交曲线坐标下三维代数应力通量模型

针对弯曲及不规则明渠的水动力及物质输运特性，本文建立了曲线坐标系下的三维代数应力通量数学模型，对平面上弯曲及不规则复杂边界情形，采用Poisson方程进行正交曲线坐标变换，各向异性的湍流代数应力通量模型被引用于本文的模拟计算中，以体现复杂边界条件引起的水动力及物质输运特性的变化。通过180度强弯曲明渠水槽及贵溪电厂不规则边界河段物理模型试验两个实例计算表明，实测值与计算吻合良好，效果令人满意。     

基于偏振光干涉仪的Interleaver解复用器实验研究

为实现更窄信道间隔的密集波分复用 ,提出了一种基于偏振光干涉仪的新型Interleaver解复用器 ,分析了结构组成与基本工作原理 ,对其进行了初步的测试实验 ,该器件所分开的DWDM系统两组波长功率均衡 ,隔离度分别为 1 0 6dB和 1 4 6 4dB ,- 1dB带宽分别为 0 7nm和 0 4nm。